![]() The details appear in the Annals of Internal Medicine. Scientists from Johns Hopkins Medicine in Baltimore, Maryland, have shown that as many as 1 in 5 RT-PCR tests for the coronavirus may produce false negatives, incorrectly informing a patient that they do not have a SARS-CoV-2 infection when they actually do. A new analysis suggests that the accuracy of RT-PCR could also be under question. There has been much discussion about the accuracy of antibody tests, with manufacturers even withdrawing some such tests due to concerns about their reliability. It allows the detection of genetic material specific to the SARS-CoV-2 virus, confirming a diagnosis of the associated disease, COVID-19.Īlthough serological, or antibody, tests are also available, these typically serve to confirm a past infection in people who have since recovered from COVID-19, rather than to detect an active infection. This analysis uses a laboratory procedure called reverse transcriptase-polymerase chain reaction (RT-PCR), which converts genetic material from the virus (RNA) to DNA before amplifying it. The majority of tests for the novel coronavirus involve taking a swab from the back of the nose or the throat for genetic analysis. Share on Pinterest New research draws attention to false-negative results of new coronavirus tests. ![]()
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